Single-player gaming lacks the peaks that you get in good multiplayer gaming. It also lacks the troughs in bad multiplayer gaming. Your gaming preferences are going to be strongly influenced by how much weight you place on the most extreme experience versus the average experience and your relative weight of positive versus negative experiences.
If one really horrible thing can ruin your entire night, PvP will almost inevitably be a harrowing experience for you, and any multiplayer gaming is a crapshoot. Beyond just the effects of anonymity, wide exposure teaches you that some people are just genuinely horrible human beings. And they want to share that with you.
If you are the sort to laugh it off or counter-troll, the downside of PvP and multiplayer gaming is limited for you. If you seek conflict rather than avoiding it, the internet will always have more for you. If you remember the positive and forget the negative, the downside is temporary while the upside is lasting.
If you evaluate the quality of the evening by how many minutes you were having a good time, something like EVE Online will rarely be a good night for you. Scouting, mining, traveling… the median minute of play is pretty dull. Granted, the average minute of MMO play is poor relative to most other niches, but PvP gaming with lengthy downtime stands out as low average quality. If you evaluate the quality of the evening by the best minute in which you were having a good time, nothing is going to top PvP and multiplayer. If you place more weight on extreme rather than average experiences, even strongly negative events can be rated highly because you take the ebb with the flow.
A related factor is the context in which you will tolerate all this. You might tolerate perverse randomization but rage against human maliciousness. You might laugh off human stupidity but rage against poor design. You might tolerate poor design as long as the company is good. Introverts will have an extra weight against negative multiplayer interactions, because those are excessively psychologically taxing.